Egg Donor Screening

Egg Donor Screening 

Donor Nexus adheres to the absolute highest egg donor screening standards in our industry. On this page, we provide an overview of the egg donor screening process with Donor Nexus.

Donor prescreen evaluations consist of:

1. Medical Evaluation

The medical evaluation is often completed on day 1, 2, or 3 of the egg donor’s menstrual cycle at the intended parent’s designated fertility clinic.* 

*If your selected egg donor lives out of state, your physician may require her to fly in for a one-day medical screening. At times, the physician will not require the donor to fly, specifically if the donor has cycled before. We will orchestrate the donor’s travel arrangements and/or any pretesting that needs to be completed at a fertility clinic close to the donor’s home.

The medical evaluation includes:

• An ultrasound assessment of the uterus and ovaries

Ovarian reserve testing: To ensure that the egg donor is a top producer of eggs, the donor has ovarian reserve testing done which consists of a blood test looking at Follicle Stimulating Hormone (FSH), Anti-Mullerian hormone (AMH) and an antral follicle count (AFC). The antral follicle count is a special ultrasound where the examiner counts the number of resting eggs the donor has. These three tests allow us to reject any egg donor not likely to have a good response to fertility medication, greatly reducing the risk of poor response or poor egg quality.

State Mandated Infectious Disease Screening & STI Testing: The egg donor is screened for HIV 1 and 2, hepatitis B, hepatitis C, HTLV 1 and 2, syphilis, chlamydia and gonorrhea as well as other health screening labs. 

Drug Screening: The egg donor is screened for drug use, including: opioids (heroine, morphine, prescription narcotics), cocaine, amphetamines and marijuana.

Genetic Carrier Panel: The egg donor is interviewed by a certified genetic counselor in order to identify egg donors that may have an increased risk for genetic diseases. The genetic counselor then recommends any specific tests needed for that specific egg donor based on her family history and ethnicity. In addition to these specific tests, the egg donor also is screened for cystic fibrosis, spinal muscular atrophy, Fragile-X, and a multitude of other genetic diseases. The results of both the genetic counselor’s report as well as the blood tests are available for review by the intended parents. Learn more.

Physical Examination: The egg donor will undergo a standard physical examination to ensure that she is healthy. We also perform a pap smear if the donor hasn’t had one done in the last 12 months. 

Consultation with the Physician or Nurse Practitioner: The donor will receive injection training to prepare for injecting medications. The donor will also be interviewed and examined by a board certified Reproductive Endocrinologist and Infertility subspecialist.

Comprehensive Medical Questionnaire: The medical questionnaire will be used to determine the family history of the donor.

2. Psychological Evaluation

The donor will have a psychological evaluation with a therapist to ensure the egg donor is emotionally ready to perform what is required of her as a donor.

3. Legal Consultation

The donor will have a legal consultation with a designated reproductive law firm gives the egg donor the opportunity to speak with an attorney to review her contract so she understands her rights and responsibilities before, during, and after her cycle.

The prescreening evaluations can take up to 2 months to complete*, depending on the donor’s menstrual cycle. The donor may or may not be put on birth control pills.

*This timeframe is only applicable to fresh egg donor cycles. If you have chosen frozen donor eggs, the screening of the contributing donor has already been completed.

Additional Resources:


If you have any additional questions, please contact us using the form below and our team will get back to you as soon as possible.


Get in Touch

We are always here to answer any questions you may have. Contact us today to start your journey!